2022 Volume 91 Issue 6 Pages 356-360
Scanning probe microscopy has been used to characterize structures and electronic properties of surfaces as well as to construct nanostructures via atom-by atom manipulation. Recent advances in tip-functionalized scanning probe microscopy allows us to measure inner structures of molecules. The bond-resolved imaging technique is of importance to investigate precursors and products during on-surface reaction. In this article, the tip-induced structural isomerization and addition reaction will be discussed.