Development of MicroLED neuroscience probe

Abstract

Optogenetic techniques, in which neural activity can be controlled by irradiating light from outside, have high temporal resolution and are used to understand brain function. In recent years, there has been a growing demand for techniques to irradiate light to multiple specific neurons spread throughout the brain tissue in order to elucidate more advanced brain functions with complex neural networks. However, it is difficult to irradiate specific areas or multiple areas simultaneously using conventional light irradiation techniques such as optical fibers or microscopes, and their use in freely behaving animals is limited. In this paper, we introduce our MicroLED neuroscience probes that can be applied to a deep brain region and a wide area of the cerebral cortex.