Abstract
One of the major criteria in developing industrial applications of sonochemistry is the optimization of various experimental factors in order to achieve maximum efficiency at a minimum energy cost. There are two key parameters that control the primary sonochemical reaction efficiency: (i) bubble temperature that determines the amount of primary radicals generated inside a single bubble and (ii) the total number of active cavitation bubbles, which determines the overall chemical activity. However, these two parameters depend upon various experimental conditions, namely, acoustic frequency, acoustic power, reactor design, etc. The chemical reactivity is also dependent upon the mass transfer events and other physical effects of acoustic cavitation. The facts and factors involved in optimizing sonochemical reactions have been discussed.