P20 Effect of organic compound addition on ultrasonic destruction of microcapsules

Abstract

A drug delivery system (DDS) helps to suppress damage to a patient's body via targeted therapy. These systems use microcapsules as one of the forms of drug delivery carriers, and ultrasound waves are used to trigger drug release from the capsules. Ultrasonic destruction of capsules has been well documented, and it is generally known that the main factor inducing destruction is cavitation bubbles.
In this study, we examined the influence of external factors on ultrasonic destruction of microcapsules. We added various organic compounds to suspensions containing the capsules and irradiated the samples with ultrasonic waves at 430 kHz and 950 kHz.