Blood Compatibility of Sol-Gel Derived Metal Oxide Layers

Abstract

We examined blood compatibility of sol-gel derived metal oxide layers. The oxide layers were subject to analyses to XPS, XRD, UV-VIS and FT-IR. Surface properties such as wettability, roughness and profile were also measured. Blood compatibility of the oxide layers was judged from platelet adhesion. The platelet adhesion was evaluated by counting the number of platelet per unit area on SEM photos taken after contacted with platelet rich plasma for 30 min. Less number of platelets adhered on titanium oxide layer than silicon or aluminum one. In conclusion, chemical composition, chemically state of the surface and thickness of the oxide layer influenced to platelet adhesion rather than wettability and surface roughness.