Bio-activation of titanium by biocomposite scaffold

Abstract

It was reported that a biocomposite scaffold (BcS) was formed on a hydroxyapatite in culture medium with fetal bovine serum, and it had an active effect on cell growth. In this study, BcS was prepared on titanium with alkali-heat treatment to induce a bioactivity. Proliferation and adhesion of osteoblast-like cells were activated on BcS. Consequently, it was suggested that BcS could be used to bioinert material as a cell active substrate and tissue-engineering scaffold.