Abstract
A bone-like apatite layer formed on a hydroxyapatite by a coprecipitation reaction reaction with a deposition of bone-like apatite and an adsorption of serum protein improved a cell growth. In this study, effects of serum protein adsorption to substrates on the formation of bone-like apatite layer and the cell response were investigated. The formation of bone-like apatite layer on a strontium-substituted apatite was confirmed, and then the cell growth on the layer was improved. Accordingly, a difference of protein adsorption to substrate had not appeared to the effect of bone-like apatite layer on the cell growth.
