Preprints of Annual Meeting of The Ceramic Society of Japan
Preprints of Fall Meeting of The Ceramic Society of Japan
Annual Meeting of The Ceramic Society of Japan, 2006
Session ID : 2P068
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Toxicological evaluation of mesoporous silica nanoparticles with in vitro test
Yuki MoriokaTakao SaitoYoshihiro Kurosawa*Katsuya KatoYoshiyuki Yokogawa
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Abstract
Four kinds of mesoporous silicates (MSPs) were prepared according to the standard methods; using by triblock copolymer P123 and silica source TEOS. Also, KCl and decane were used to control the pore size and diameter of MPSs. The cytotoxicology of the MPSs was tested with the co-culture of various concentration of MPSs and osteoblastic cell MC3T3-E1 Cell. The cell number was counted by the measurement of oxide-reductase of the cell. The amino-substituted MSPs showed high toxicity with low concentration of the nano-particle (0.1 mg /ml).
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© The Ceramic Society of Japan 2006
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