Abstract
Four kinds of mesoporous silicates (MSPs) were prepared according to the standard methods; using by triblock copolymer P123 and silica source TEOS. Also, KCl and decane were used to control the pore size and diameter of MPSs. The cytotoxicology of the MPSs was tested with the co-culture of various concentration of MPSs and osteoblastic cell MC3T3-E1 Cell. The cell number was counted by the measurement of oxide-reductase of the cell. The amino-substituted MSPs showed high toxicity with low concentration of the nano-particle (0.1 mg /ml).