Abstract
We have succeed in development of the novel apatite cement using hydroxyapatite (HAp) particles surface-modified with inositol phosphate (IP6). In the present investigation, biological apatite powder (hereafter, bone HAp) instead of pure HAp was used as a starting powder for the chelate-setting cement. The bone HAp powders including various bone minerals, Na+, K+, Ca2+, Mg2+, F-, PO42-, and CO32-, were synthesized via conventional wet process. The compressive strength derived from bone HAp powders surface-modified with IP6 (IP6-Bone HAp) attained maximum ~16 MPa in the case of the powder/liquid ratio = 1/0.40 [w/w]. This value was comparable to the compressive strength of IP6-HAp cement fabricated under the same conditions.