Abstract
Amorphous calcium phosphate (ACP) is one of the precursors of hydroxyapatite (HAp) at wet synthesis. ACP transform into low crystalline HAp at body temperature. The low crystalline HAp is bone-like apatite. Thus, when low crystalline HAp cement body can be prepared about 0ºC, this body is expected to be a controlled released material. In this study, behavior of these cement bodies in a body environment was investigated. We prepared cement bodies from ACP and from calcium phosphate cement (CPC) consisting of calcium hydrogenhposphate dihydrate (DCPD) and tetracalcium phosphate (TTCP). After soaking in simulated body fluid (SBF) for 7 days, cement body from ACP was broken, and the weight of cement body from CPC decreased. These cements have a potential of drug controlled release material.
