Abstract
Ceramic biomaterials are widely used for biomedical applications, such as artificial bone due to their biological affinity to living bone. Fundamental understanding of the reaction between ceramics and simulated body fluid leads to development of highly functionalized biomaterials through techniques implying surface modification of titanium metals for providing bioactivity, synthesis of bioactive organic-inorganic hybrids, biomimetic synthesis of composites, and fabrication of calcium phosphates with designed microstructure through hydrothermal and gel-mediated methods.