1999 Volume 1 Issue 1 Pages 45-51
Maintaining the room pressure is essential for preventing contamination during pharmaceutical operations. Among the factors affecting the room pressure, the control functions were discussed. We stressed that in order to improve the quality of room pressure control, a constant air volume unit of higher accuracy and stability should be employed; the pressure control should not be sensitive to over-integration even after a long lasting deviation; the necessary facility design is such that the air balance in the room should not be drastically changed; special considerations should be given when determining the position of louvers, the definition of reference pressure, and duct geometry; and a computer-based integral management for the entire parts of automatic controls should be employed.
