NHPH感染胃MALTリンパ腫の2例

高木 亮輔; 岩本 淳一; 小宮山 夏永; 中川 俊一郎; 森山 由貴; 柿崎 文郎; 玉虫 惇; 門馬 匡邦; 小西 直樹; 屋良 昭一郎; 平山 剛; 池上 正; 森下 由紀雄; 中村 正彦

doi:10.11641/pde.106.1_55

Two cases of gastric MALT lymphoma caused by NHPH

Ryosuke Takagi, Junichi Iwamoto, Natsue Komiyama, Shunichiro Nakagawa, Yuki Moriyama, Fumio Kakizaki, Makoto Tamamushi, Tadakuni Monma, Naoki Konishi, Shoichiro Yara, Takeshi Hirayama, Tadashi Ikegami, Yukio Morishita, Masahiko Nakamura

Author information

Ryosuke Takagi
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Junichi Iwamoto
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Natsue Komiyama
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Shunichiro Nakagawa
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Yuki Moriyama
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Fumio Kakizaki
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Makoto Tamamushi
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Tadakuni Monma
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Naoki Konishi
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Shoichiro Yara
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Takeshi Hirayama
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Tadashi Ikegami
Department of Gastroenterology and Hepatology, Tokyo Medical University, Ibaraki Medical Center
Yukio Morishita
Diagnostic Pathology Division, Tokyo Medical University, Ibaraki Medical Center
Masahiko Nakamura
Tokai University School of Medicine

JOURNAL RESTRICTED ACCESS

2025 Volume 106 Issue 1 Pages 55-57

DOI https://doi.org/10.11641/pde.106.1_55

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Abstract

We report cases of gastric mucosa-assisted lymphoid tissue (MALT) lymphoma caused by Non-Helicobacter pylori Helicobacter (NHPH). Case 1: A male in his 60s underwent an endoscopic examination that revealed a faded depressed surface in the hypogastric fold. Histological analysis established a diagnosis of MALT lymphoma. PCR test was positive for H. heilmannii (s. s.) and negative for H. pylori. Endoscopic findings improved with eradication, and the histology of MALT lymphoma disappeared. Case 2: A 60s woman was diagnosed with gastric MALT lymphoma. PCR test was positive for H. suis and negative for H. pylori. Endoscopic findings did not resolve the MALT lymphoma findings after eradication. The addition of radiotherapy resulted in the disappearance of both endoscopic and histological findings of MALT lymphoma.

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