Abstract
Helicobacter pylori (Hp) infection, gastroduodenal disease and gastric mucosa in Vietnamese were studied comparing with Japanese. We used 516 cases of Vietnamese, examined by ourselves in Ho Chi Minh City, and 1,994 cases of Japanese diagnosed by the same criteria.
1) According to the comparison of Hp infection rate between Vietnamese and Japanese after match of age, sex and endoscopic diagnosis, an infection rate of Vietnamese was significantly lower than that of Japanese (Vietnamese : 51.9%, Japanese : 74.4%, p＜0.00001) .
2) Glandular atrophy score in specimen No.3 (the lesser curvature of the lower body) , taken in accordance with triple site gastric biopsy, and endoscopic gastric mucosa score in the lesser curvature of the lower body were low in Vietnamese compare with Japanese. Intestinal metaplasia score at the point of No.1 (the gretaer curvature of the lower antrum) , No.2 (the greater curvature of the upper body) and No.3 were higher in Japanese than in Vietnamese. It was revealed that atrophic change and intestinal metaplasia by Hp infection were particular changes to Japanese.
3) Pepsinogen (PG) I/II ratio of Japanese was lower than Vietnamese (each 4.3, 4.7, p＝0.0193) . It was also recognized in Japanese and Vietnamese that PGI/II ratio of Hp positive cases was lower than that of negative cases.
