Abstract
A 68-year-old man was seen at the hospital because of right abdominal palpable mass. A barium enema study showed an apple-core-sign of the ascending colon, and an abdominal CT showed multiple liver metastases and mass of right lower abdomen. Due to appearing of ileus, right hemicolectomy was performed with a diagnosis of the ascending colon cancer with multiple liver metastases. Histlogically, the tumor consisted of polygonal-shaped cells and grew in a solid pattern without grand formation. Immnohistochemically, tumor cells were positive for Chromogranine A and NSE. Electron-microscopically, these cells contained abundant neuroendocrine granules in cytoplasm, and diagnosis of endocrine carcinoma was made. Histologically, in addition to operation, intestive treatment with chemotherapy and radiotherapy are necessary for patients with colorectal endocrine cell carcinoma.
