Abstract
Difference of gastroduodenal disease between patients with hemodialysis and control group (non-hemodialisys patients) was studied by the match of age and gender. Helicobacter pylori (Hp) infection between two groups was also compared by the match of age, gender and endoscopic diagnosis.
1) We found many gastritis cases (36.6%) , which means redness, erosion, hemorrhagic erosion and edema, and a few peptic ulcer cases (7.3%) in hemodialysis group. In control group, there were many peptic ulcer cases (42.7%) and a few gastritis cases (11.0%) . There were differences in these two groups.
2) A prevalence of Hp infection in hemodialysis group was significantly low compare with control group (hemodialysis group : 28.6%, control group : 71.4%, P＜0.001) . A prevalence of Hp infection in shorter than 3 months hemodialysis group showed 31.3% and it became lower percentage as hemodialysis period became longer.
3) An average of chronic inflammation score in Hp negative hemodialysis group was higher than that of Hp negative control group (0.81 and 0.30, respectively, P＝0.001) . A prevalence of serum anti-HpIgG antibody was also high in Hp negative hemodialysis group compare with Hp negative control group (hemodialysis group : 58.3%, control group : 20.0%, P＜0.05) . According to these results, there was a possibility of natural eradication cases in patients with chronic renal failure.
