A case of multifocal adenocarcinoma with Ill-de-fined margin arising from long segment barrett's esophagus

Abstract

A 73-year-old woman had been made a diagnosis that she had gotten reflux esophagitis and Long-Segment Barrett's Esophagus (LSBE) . However, it turned out to be the cancer due to the re-examination of endoscope after a year and two months from the first diagnosis. Although it had been thought to be mucosal cancer because there had been no unevenness of mucous membrane, histological examination after operation revealed that it was multifocal minimal cancers arised from Barrett's esophagus. Recently, the theory of dysplasia-cancer sequence is worldwidely accepted, in this case it is interesting that we could find out the initial appearance of carcinogenesis in the LSBE. We must take the contrast method with indigocarmine to find out very small cancer.