Progress of Digestive Endoscopy
Online ISSN : 2187-4999
Print ISSN : 1348-9844
ISSN-L : 1348-9844
Case report
Two cases of acute Helicobacter pylori infection with negative results of 13C-urea breath test
Yoshihisa UritaKazuo HikeNaotaka ToriiYoshinori KikuchiHidenori KurakataEiko KandaMasahiko SasajimaMotonobu OzakiKazumasa Miki
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2003 Volume 63 Issue 2 Pages 102-103

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Abstract
A 45-year-old male visited our hospital with a complaint of epigastralgia. He underwent upper endoscopy for gastric cancer screening before 7 days. At endoscopy, hemorrhagic gastritis was found in the distal stomach. RUT and endoscopic UBT were positive, but conventional UBT kept the negative results for 15 weeks. Since changes of serum pepsinogens, suggesting the inflammation of the gastric mucosa by H. pylori,had been found, eradication therapy was carried out.
A 56-year-old male underwent screening endoscopy and did not have any abnormal findings. After 10 days, he complained of epigastralgia and visited our hospital. Hemorrhagic gastric erosions with evidence of bleeding were seen in the antrum and the duodenal bulb. He had the negative results of UBT, and the UBT result became positive after 5 weeks. From the clinical courses of these two cases, it is suggested that UBT is not sensitive for detection of acute H. pylori infection.
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© 2003 Japan Gastroenterological Endoscopy Society Kanto Chapter
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