A case of colonic ulcers in patient With Schönlein-Henoch purpura

Abstract

A 72-year-old male was admitted to our hospital, complaining melena, abdominal pain and purpuric rash appeared in the bilateral lower legs. The colonoscopy demonstrated multiple ulcers from the cecum through the rectum. Histological specimens taken from the margin of ulcers revealed non-specific inflammation. No pathogen was confirmed in physiological and immunochemical findings. Cutaneous biopsy showed leukocytoclastic vasculitis. He was treated with total parenteral nutrition and intravenous injection therapy of predonisolone under a diagnosis of Schönlein-Henoch purpura. The symptom and purpura improved in 3 days and in 2 weeks.
We investigated 55 reports of adult patients with Schönlein-Henoch purpura with apparent digestive lesions during last 11 years. We confirmed that the colonic ulcers with edema were specific involvements of Schönlein-Henoch purpura.