Progress of Digestive Endoscopy
Online ISSN : 2187-4999
Print ISSN : 1348-9844
ISSN-L : 1348-9844
Case report
A case of predominat proximal colon polyposis
Masakatsu FukuzawaTetsuo NakamuraShiniti TakagakiKenji NukagaKouhei KawakamiTadashi HagiwaraSatoru TairaMasaaki MiyaokaKazuo TamuraFuminori Moriyasu
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Keywords: AFAP
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2004 Volume 64 Issue 2 Pages 110-111

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Abstract

We descride a 63-year-old man, who turned out to be positive for fecal occult blood test on November, 2001. Colonoscopy was carried out on May 2002, and there were multiple polypoid lesions predominantly in proximal colon. On February 2003, Endscopic mucosal resection (EMR) of Isp'polyp (12mm in size) , LST (granular type ; 16mm in size) both located in ascending colon was perforemed. Pathological findings revealed carcinoma in adenoma in both resions. In recent years, attenuated familial adenomatous polyposis (AFAP) attract a great deal of attention. The mutations in APC and MYH gene are reported to be associated with AFAP. We analyzed mutation of APC and MYH gene. In this case, no mutation of both gene was detected. We report a rare case of colon poilyposis resembling AFAP.

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© 2004 Japan Gastroenterological Endoscopy Society Kanto Chapter
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