Nasobiliary drainage and percutaneous injection sclerotherapy with minocycline for obstructive jaundice due to polycystic liver disease : A case report

Abstract

Polycystic liver disease is confirmed in 0.1-0.5% of adults examined at autopsy. Most of them present with a subclinical form of the disease while alive. This time, we experienced a rare case of a patient with polycystic liver disease complicated by obstructive jaundice. To our knowledge, only 14 such cases have been reported. In general, the treatments include operation (fenestration and/or cyst resection), biliary drainage (percutaneous or endoscopic), and percutaneous injection sclerotherapy. Our case was complicated by severe acute cholangitis, and therefore, we first performed emergency nasobiliary drainage. Thereafter, we performed percutaneous injection sclerotherapy with minocycline. Because of absence of intracystic bleeding or infection, it was difficult to identify the cysts that resulted in obstructive jaundice. However, with the aid of a nasobiliary drainage tube, we successfully punctured the cysts that caused obstructive jaundice.