2014 Volume 85 Issue 1 Pages 36-39
Familial adenomatous polyposis (FAP) manifests occasionally as a gastric epithelial tumor. It is important to diagnose the tumor at an early stage for less invasive treatment. In this study, we examined the usefulness of magnifying endoscopy with narrow-band imaging (ME-NBI) for examining gastric epithelial tumors in patients with FAP. Four FAP patients with gastric epithelial tumors underwent ME-NBI and subsequently, endoscopic resection of the lesions. There were 8 lesions (3 adenoma, 5 cancer) in the four patients. We enrolled these patients into the present retrospective study.
We analyzed the ME-NBI findings using the 'VS classification system’ and compared them with the pathological findings after endoscopic resection.
A demarcation line was observed clearly in all the lesions, and an irregular vascular pattern was recognized in all the cancer lesions. Two of the 3 adenoma lesions had regular microvascular and microsurface patterns. There was only 1 lesion in which the ME-NBI findings did not match the pathological findings. Thus, the concordance rate between the ME-NBI findings using the VS classification and the pathological findings was 87.5%. Although there are some limitations of this study, we think that ME-NBI for FAP patients with gastric epithelial tumors is useful for establishing a qualitative diagnosis.