2017 Volume 91 Issue 1 Pages 72-75
Histopathological diagnosis of malignant biliary strictures often have difficulty, because sampling is not easy. Thus we have sought to improve the accuracy by combining transpapillary biliary cytology, brushing cytology, and bile duct biopsy. We conducted a retrospective study to assess the diagnosability in 41 patients with malignant biliary strictures. Diagnostic accuracy was compared among the specimens from transpapillary aspiration cytology, brushing cytology, bile duct biopsy, biliary cytology immediately after brushing, and cytology of bile previously collected via endoscopic nasobiliary drainage (ENBD) . Bile duct biopsy had the highest rate of diagnostic accuracy at 85.7%, and cytology of bile previously collected via ENBD had the lowest rate at 25.0%. Bile duct biopsy was most useful for diagnosis of malignant biliary strictures. However, use of Endoscopic ultrasound-guided fine needle aspiration biopsy and biopsy under peroral cholangioscopy was to be considered for the difficult cases in collectingspecimens.
