Two patients with gastric adenocarcinoma of fundic gland type (GAFG) who previously underwent endoscopic submucosal dissection (ESD) for a common type of gastric carcinoma.

Abstract

【Case1】An 83-year-old man was diagnosed with signet ring cell carcinoma and underwent ESD. Helicobacter pylori eradication therapy was performed after ESD. A whitish flat lesion with dilated vessels was found five years later. Biopsy examination revealed irregular fundic glands, and we performed ESD. Pathological examination demonstrated GAFG, Type 0-IIb.

【Case2】A 59-year-old man was diagnosed with signet ring cell carcinoma and underwent ESD. Both gastric mucosal atrophy and Helicobacter pylori antibody in serum were negative. A whitish flat lesion with a black pigment point was found one year later. Biopsy examination revealed irregular fundic glands, and we performed ESD. Pathological examination demonstrated GAFG, Type 0-IIc.