2020 Volume 96 Issue 1 Pages 181-182
A 66-year-old man visited our hospital complaining of anorexia and hair loss. Upper gastrointestinal endoscopy revealed polyposis with redness throughout the gastric mucosa. Colon scopy also showed polyposis over the entire colon and was complicated by sigmoid colon cancer. On pathological examination, mucous lamina propria was accompanied by cystic dilation of the gland, mucosal edema, inflammatory cell infiltration, and it was a diagnosis of hamartomatous polyps. Based on the above, the patient was diagnosed with Cronkhite-Canada syndrome complicated with colon cancer. Steroid treatmet was started after surgical treatment for colon cancer. After the start of steroid treatment, gastrointestinal tract lesons, alopecia and anorexia was improved. Since steroid treatment was gradually reduced and remission was made, steroid treatment was terminated. However gastrointestinal tract lesions and alopecia worsened, steroid treatment was resumed, and treatment is continued now. Discontinuation and low-dose maintenance of steroid in treatment of CCS have not been clarified in previous studies.
This case report may indicate that the maintenance treatment with low-dose steroid is nessesary for remission of CCS.
