Case Report
A case of Helicobactor pylori negative nodular gastritis accompanied by eosinophilic esophagitis
2020 Volume 96 Issue 1 Pages 95-97
Details
2020 Volume 96 Issue 1 Pages 95-97
A 34-year-old man visited my clinic for the symptoms of GERD. He has allergies including food and had a dog as a pet.
Upper gastrointestinal endoscopy revealed nodular mucosa in the gastric antrum and the presence of linear furrows and bamboo-joint like appearance throughout the esophagus. In blood biochemistry, IgE RAST of crustacea was positive; H. pylori IgG antibody and Urea Breath Test were negative.
Histopathological findings showed eosinophil infiltration of more than 40 / HPF in the esophageal mucosa and chronic active gastritis with lymphoid follicles with large helical bacilli with Gimenes staining. He was diagnosed with H. heilmannii-like Organism (HHLO) nodular gastritis accompanied by eosinophilic esophagitis (EE). He was prescribed oral proton pump inhibitor and fluticasone inhalation which resulted in improvement of endoscopic and histologic findings.
Reports of HHLO nodular gastritis accompanied by EE are rare. Therefore, this case is considered to have some clinical significance in H. pylori negative era.
