A case of a mixed neuroendocrine-non-neuroendocrine neoplasm of pancreas

Abstract

A 71-year-old man was admitted to seek a diagnosis for a 20 mm-diameter nodule at the pancreatic body which revealed no enhancement in dynamic CT scan. Under the suspected diagnosis of pancreatic cancer, we performed laparotomy to resect the tumor. As two hepatic nodules were incidentally detected and their pathological diagnosis during surgery suggested adenocarcinoma, we closed the abdomen without resection. However, the final pathological diagnosis turned out to be neuroendocrine cancer (NEC). We performed endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for the pancreatic tumor, which revealed adenocarcinoma. Therefore, we finally made a diagnosis of a mixed neuroendocrine-non-neuroendocrine neoplasm of pancreas.