2021 Volume 99 Issue 1 Pages 76-78
The rate of local recurrence of esophageal cancer after chemoradiotherapy (CRT) remains high despite its demonstrated utility in treatment. Local recurrent lesions after CRT are treated with surgical and endoscopic interventions, however, surgical approaches are associated with high postoperative mortality rates. Recent studies reported the utility of endoscopic submucosal dissection (ESD) for locally recurrent lesions after CRT. We herein report two cases (both 71-year-old men) of clinical Stage I squamous cell carcinoma that were treated with CRT and then ESD for local recurrences. Although the patients achieved a complete response following CRT, local recurrences were observed 4 months and 5 years later. ESD was used to achieve complete resections in both patients without any adverse events. An endoscopic ultrasound with a miniature probe was useful for performing salvage ESDs. There were no lesion recurrences at 15 months and 18 months after the post-ESD.
