Abstract
A very rare case of primary signet-ring cell carcinoma at an early stage of the colon is reported.
A 77-year-old male visited to our hospital because of immunologically positive fecal occult blood test. Colonoscopic examination revealed a flat elevated lesion with central depressed area at the hepatic flexure. Biopsied specimen demonstrated signet-ring cell carcinoma, and right hemicolectomy was undergone. Resected material revealed a IIa+IIc like lesion, measuring 20 mm in diameter. Histologically, signet-ring cell carcinoma diffusely infiltrated into the deeper part of submucosal layer and invaded to the lymphatic vesseles. However, neither lymph node nor distant metastasis was observed. He is still alive in good health 2 years after the operation.
