2000 Volume 56 Issue 2 Pages 68-69
A 56-year-old man was admitted to our hospital because of tarry stool. He had experienced resection of a nasal malignant melanoma at the age of 52. Radiographic and endoscopic examination revealed a submucosal tumor with deep ulcer at the 2nd portion of the duodenum. Pathological findings of the biopsy specimen from the tumor showed amelanotic malignant melanoma. Even though partial melanin pigmentation was seen in the past resected specimen from the nasal cavity pathologically, the duodenal lesion was considered as metastasis. In addition, multiple metastases to the bilateral adrenal glands and the cerebrum were noticed by CT scan examination. Gastrointestinal metastasis of malignant melanoma is sometimes found at autopsy, but it is rare to be diagnosed because it develops rarely as a digestive symptom. It is thought that this case is interesting because metastatic lesion of the duodenum was recognized radiographically and endoscopically.
