Abstract
Localized aggressive periodontitis is a rare condition characterized by rapid periodontal destruction around the first molars and incisors in systemically healthy individuals with little or no accumulation of visible plaque and/or calculus. This report describes a patient diagnosed as having localized aggressive periodontitis treated with several periodontal regeneration techniques. A 20-year-old female presented with clinical and radiographic evidence of severe attachment loss around the first molars, incisors, and right upper first premolar. Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans, and Tannerella forsythensis were detected from the subgingival microflora using the multiplex polymerase chain reaction method. The periodontal surgical procedures consisted of autogenous bone graft alone, guided tissue regeneration technique, and autogenous bone graft combined with enamel matrix derivative or platelet-rich plasma. Those procedures resulted in 2-4 mm of clinical attachment gain with minimal postoperative gingival recession. Two-year follow-up revealed that the destructive lesions were successfully treated.