Abstract
For the treatment of patients with aggressive periodontitis, a thorough control of the infection is required to reduce the disease activity. Detection of periodontal pathogens by a polymerase chain reaction-based method or measurement of the serum IgG antibody titers by enzyme-linked immunosorbent assay are now widely used for microbiological diagnosis and assessment of the disease activity. We report the case of a 25-year-old woman with impaired neutrophil phagocytosis ability who suffered from generalized aggressive periodontitis . After the initial periodontal treatment and periodontal regenerative surgery, she received the final prosthodontics, and supportive periodontal treatment (SPT) was initiated. For over a decade, from the beginning of the treatments, the clinical parameters and serum titers of IgG periodontal pathogens have been monitored, and the relationships between the twoanalyzed. During the SPT, recurrence and progression of periodontitis was seen around site 26, despite maintenance of a stable periodontal condition at other sites. The serum IgG antibody titers against periodontal pathogens were elevated in parallel with the progression of periodontitis at site 26. In the present case of generalized aggressive periodontitis, the serum IgG antibody titers reflected the disease activity of periodontitis even around a single tooth, suggesting the usefulness of the examination for assessment of the disease activity. Nihon Shishubyo Gakkai Kaishi(J Jpn Soc Periodontol)54(2):193-202, 2012
