Abstract
Herein, we report a case of gingival overgrowth related to immunosuppressant and calcium channel blocker medications, which was successfully treated by non-surgical periodontal therapy. The patient（a 34-year-old woman）presented with a chief complaint of gingival swelling. She had been receiving cyclosporine A following kidney transplantation, along with cilnidipine and biaspirin for the prevention of possible complications. She was also clinically diagnosed as having chronic periodontitis, with a mean probing depth（PD）of 6 mm; the PD was 4-6 mm at 31% of the sites, and ≥7 mm at 60% of the sites. With the initial periodontal therapy consisting mainly of plaque control and scaling and root planing（SRP）and then subsequent re-SRP, marked reduction of the gingival overgrowth was observed, concurrently with improvement of the gingival inflammation. After this treatment, none of the sites showed a PD of ≥5 mm. It has been 10 months since the implementation of the supportive periodontal therapy, and the periodontal condition has remained stable. Since the gingival overgrowth in the present study was accompanied by edematous swelling of the gingiva induced by inflammation, the treatment effort consisting of plaque and calculus control and oral hygiene instructions was thought to have contributed to the improvement of the gingival condition in this patient. It is now necessary to continuously monitor the status of plaque control in the maintenance program. Nihon Shishubyo Gakkai Kaishi (J Jpn Soc Periodontol) 56(1)：72-81, 2014.
