Abstract
The histamine contents in dental plaque collected from patients with periodontal disease were measured by Hakanson & Rönnberg method, and compared with various clinical findings such as simplified gingival index, debris index, calculus index, depth of periodontal pocket, degree of bone loss and teeth mobility.
The following results were obtained;
1. The histamine contents in detal plaque of all subject were able to measure in the range of concentration from 0.7 to 5.3μg/wet weight mg.
2. The histamine contents in dental plaque had a tendency to increase according to the progression of simplified gingival index score.
3. The histamine contents was decease with the increase of debris index score.
