Immunological Study on Serum of Patients with Periodontal Disease

II. Relationshipes between Its Classfication (Degree, Type) and Immunoglobulin, Complement Contents

Abstract

The patients with periodontal disease were divided into mild, moderate and severe case and also divided into inflammatory and dystorophic type. Serum immunoglobulin and complement (C₃) value were measured in these groups.
The salient findings were as follows:
1) In the mild cases, the IgG level was higher than in the healthy adults. (p≤0.002)
2) In the moderate cases, the IgM level was higher than in the healthy adults. (p≤0.005)
3) In the severe cases, the IgG and IgA levels were higher than in the healthy adults (p≤0.002, p≤0.05) and C₃ level was lower than in the healthy adults. (p≤0.002)
4) In the inflammatory type, the IgG and IgM levels were higher than in the healthy adults. (p≤0.02, p≤0.1)