Abstract
Cathepsin D and elastase activiies in gingival fluid and in saliva collected from patients with periodontal disease were measured using acid denatured hemoglebin and N-Succinyl-L-alanyl-L-alanyl-L-alanine-p-nitroanilide and compared with the clinical fiindings such as PMA-index and pocket depth. Acid phosphatase activity, fluid weight, quantity of protein in fluid and occult blood in saliva were also measured.
Stastically signifcant correlations were found between these protease activities and PMA-index, as well as pocket depth. These protease activities in gingival fluid and in saliva were also correlated.
The activities of cathepsin D and elastase were seemed to reflect the degree of periodontal disease as well as acid phosphatase activity.
