Clinical Evaluation of Pasta Drug, ACESS-A, on Gingivitis and Marginal Periodontitis by Double Blind Method

Abstract

The clinical effect of Acess-A on gingivitis and marginal periodontitis was determined by a double blind method using an inactive placebo as a control. The results are as follows:
(1) Total clinical findings, symptoms antoanalyzed by patients and observations by physicians in charge, indicated a trend that Acess-A possessed better improvement than the control.
(2) In case of main clinical findings, the observations by physicians in charge such as redness, swelling, bleeding, and pus discharge, a significant improvement (p<0.05) by Acess-A was confirmed 4 weeks after the initiation of pasta application in effective percentage.
(3) Significant improvements in recoveries of oral feeling autoanalyzed by patients and of dental calculus, redness, swelling, and bleeding observed by physicians in charge, were recognized with Acess-A in improvement rate.
(4) In order to reduce 50% of the observations in redness, swelling, and bleeding, Acess-A and placebo required 3-4 weeks and 4-7 weeks, respectively.
(5) No remarkable side effect was observed in both Acess-A and placebo.