Bactericidal Effects of Povidone-Iodine Solution to Oral Pathogenic Bacteria in vitro

Abstract

Seven species (Bacteroides gingivalis, Bacteroides intermedius, Bacteroides rnelaninogenicus, Fusobacterium nucleatum, Actinobacillus actinomycetemcomitans, Capnocytophaga sp, Eikenella corrodens) as periodontal pathogenetic bacteria and two control species (Streptococcus intermedius, Pseudomonas aeruginosa) were selected in order to study the bactericidal effects of 10% povidone-iodine solution (PVP-I) in vitro.
Povidone-iodine was diluted 100. , 400. , 800. , 1, 600. , 3, 200. , 6, 400. and 12, 800. and contact times were 15 sec, 30 sec and 60sec.
Strongest bactericidal effects on the seven periodontal pathogenic bacteria and two control bacteria were seen at a dilution of 400. and contact time of 15sec.
Based on these findings, we advocate 0.25% PVP-I for oral mucosa and periontal pocket irrigation .