Clinical Evaluation for Collagen Membrane (BioMendTm) in Guided Tissue Regeneration

Abstract

The purpose of this study was to evaluate the effects of absorbable collagen membrane (BioMend™) on treatment of infrabony defects and class II furcation defects. Fifty-five systemically healthy patients were treated by guided tissue-regeneration (GTR) technique using a type I bovine collagen membrane (Bio Mend™). Clinical measurements including probing depth (PD), gingival recession (GR), clinical attachment level (CAL) and mobility were obtained on the day of surgery and 3 and 6 months postsurgery . Radiographs were taken on the day of surgery and 6 months postsurgery and radiographic bone loss was calculated. The results of this study indicate that at 3 and 6 months postsurgery a significant decrease of PD (3.0mm and 3.2mm) and increase of CAL (2.5mm and 2.7mm) had occurred compared to the presurgery status. GR at 3 and 6 months postsurgery was 0.6mm. Bone loss improved significantly (7.9%). Membrane exposures were noted in 9 cases at 1 week, 6 cases at 2 weeks and 3 cases at 4 weeks after surgery. No foreign body reaction was observed during this study. This study suggests that use of absorbable type I bovine collagen membrane (Bio Mend™) may have beneficial effects for the GTR technique. J. Jpn. Soc. Periodontol., 41: 321-330, 1999.