Abstract
The purpose of this study was to investigate the effect of porous xenographic bone with a collagen barrier membrane on the formation of a new cementum and new bone in experimental intrabony defects of dogs. After extraction of the mandibular third premolar (P 3), surgical defects were created and inflammation was induced by placement of a steel braid. Four weeks later, the braid was removed. The lesions were treated by either guided tissue regeneration with a collagen membrane (control group) or a collagen membrane with porous xenographic bone (experimental group). After eight weeks, the animals were sacrificed and the tissues were histologically examined. New cementum with inserting collagen fibers was observed on the exposed surfaces in both groups. The amount of new bone was significantly greater in the experimental group than in the control group. However, the amount of new cementum formation in the two groups was not significantly different. These results indicate that the use of the bioresorbable barrier in combination with the porous xenographic bone graft material may enhance new bone and cementum formation. J. Jpn Soc. Periodontol., 42: 71-81, 2000.
