A Case of Cancer-associated Thrombosis (CAT) Due to Endometrial Cancer Discovered by Lower Leg Edema

Abstract

We encountered a case of cancer-associated thrombosis (CAT) due to endometrial cancer discovered by lower leg edema. A woman in her 40s was referred to our hospital due to left limb deep vein thrombosis and pulmonary thromboembolism. Endometrial cancer was suspected, and thrombus from the left common iliac vein to the popliteal vein, pulmonary thromboembolism, bilateral ovarian enlargement, intrapelvic lymphadenopathy, and paraabdominal aortic lymphadenopathy were confirmed based on an imaging examination. Based on these findings, we diagnosed the patient as endometrial cancer with CAT. After treatment with heparin, she started taking edoxaban 60 mg. Malignant tumors and venous thrombosis are strongly related. The accumulation of further cases is necessary to achieve the early detection of CAT and the establishment of treatment method.