A Long-Time, High Spatiotemporal Resolution Optical Recording System for Membrane Potential Activity via Real-Time Writing to the Hard Disk

Akihiko Hirota; Shin-ichi Ito

doi:10.2170/physiolsci.TN003006

Technical Note

A Long-Time, High Spatiotemporal Resolution Optical Recording System for Membrane Potential Activity via Real-Time Writing to the Hard Disk

Akihiko Hirota, Shin-ichi Ito

Author information

Keywords: long-duration recording, optical recording, real-time writing technique, photodiode array, voltage-sensitive dye

JOURNAL FREE ACCESS

2006 Volume 56 Issue 3 Pages 263-266

DOI https://doi.org/10.2170/physiolsci.TN003006

View "Advance Publication" version (May 27, 2006).

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Abstract

Using real-time hard disk recording, we have developed an optical system for the long-duration detection of changes in membrane potential from 1,020 sites with a high temporal resolution. The signal-to-noise ratio was sufficient for analyzing the spreading pattern of excitatory waves in frog atria in a single sweep.

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