Stimulation of the Nucleus Basalis of Meynert Produces an Increase in the Extracellular Release of Nerve Growth Factor in the Rat Cerebral Cortex

Abstract

Cerebral cortical extracellular NGF was collected and measured every 100 min using microdialysis and ELISA in anesthetized rats. The NGF level, which was stable at rest, increased in the ipsilateral cortex at 200–500 min after the end of focal electrical stimulation to the unilateral NBM for 100 min.