The Journal of Clinical Pediatric Rheumatology
Online ISSN : 2434-608X
Print ISSN : 2435-1105
A boy with IgA vasculitis that resembled sepsis with pyrexia and elevated level of acute-phase reactants : A case report.
Kazushi TsurugaAzusa SugitaMaki MatsumotoAyaka FujiokaAkira SatoTakumi SatoKazuhiko Sugimoto
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2020 Volume 11 Issue 1 Pages 67-71

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Abstract
We report the case of a 4-year-old boy with IgA vasculitis who developed a recurrence of IgA vasculitis 6 months after its first episode. He had a high fever, severe abdominal symptoms, arthralgia, and a marked increase in serum C-reactive protein(CRP) level (up to 22.18mg/dL). Thus, differentiation from sepsis was needed. Abdominal sonography revealed thickening of the small intestinal wall, enlarged mesenteric lymph nodes, and elevated echogenicity of mesenteric adipose tissue in the lower right abdomen. He was diagnosed as having mesenteric lymphadenitis and panniculitis caused by recurrence of IgA vasculitis, which required prednisolone administration. As sepsis could not be ruled out, an antibacterial drug was administered after blood culture. Palpable purpura was observed in his lower extremities after the clinical features promptly improved. We speculate that the patient’s high fever and elevated serum CRP level resulted from the formation of mesenteric lesions after the breakdown of the gut barrier by IgA vasculitis.
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© 2020 Pediatric Rheumatology Association of Japan
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