Abstract
Phosphorylation of D-glucose has been achieved using inorganic diimido-cyclo-triphosphate in aqueous solution. In the phosphorylation of D-glucose and maltose, 1-O-diimidotriphospho-β-D-glucose and 1-O-diimidotriphospho-β-maltose were stereoselectively synthesized with yields of 35 and 30 %, respectively. For α-cyclodextrin, γ-cyclodextrin, and mono-6-O-α-maltosyl-β-cyclodextrin, two phosphorylated products were obtained in each cyclodextrin and main products were mono-2-O-diimidotriphosphoryl esters of cyclodextrin.
