Phosphorus Research Bulletin
Online ISSN : 1882-2363
Print ISSN : 0918-4783
ISSN-L : 0918-4783
SINTERING AND OSTEOCLAST BEHAVIOR OF CARBONATE APATITE CERAMICS
Takanori WataraiMiho NakamuraNaohiro HoriuchiKazuaki HashimotoAkiko NagaiKimihiro Yamashita
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2012 Volume 27 Pages 45-49

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Abstract
B-type carbonate apatite (CA) substituting for phosphate ions, is the major inorganic components of vertebrate bones. CA is more biodegradable than HA and has been expected as a next generation biomaterial. We had reported that the polarized HA could promote bone healing. The purpose of this study was to investigate the effects of the electrically polarization on CA characterization. CA synthesized by wet method was sintered at various temperatures in carbon dioxide atmosphere. The TG measurement and polarization treatment of the sintered CA were performed. From the results of XRD and FT-IR analyses, CA was inclusion of contain carbonate about 5wt%. From TSDC measurement, the quantity of accumulated charges of CA was larger than HA. In addition, we evaluated the osteoclast behaviors on non-polarized CA and polarized CA. From the observation of cell morphology, there were multinucleated cells having actin ring structures specific for the activated osteoclasts on the CA surfaces.
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© 2012 Japanese Association of Inorganic Phosphorus Chemistry
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