INCREASE IN THE AMOUNT OF ADSORPTION OF SODIUM CHONDROITIN-6-SULFATE ON HYDROXYAPATITE OWING TO THE VOLUME EFFECT OF POLYMER COIL OF NON-ADSORBABLE POLYMER, POLYVINYLPYRROLIDONE

Abstract

Sodium chondroitin-6-sulfate (Na₂Chs) was adsorbed by hydroxyapatite (HAP), while polyvinylpyrrolidone (PVP) was not. When these polymers were mixed in an aqueous phase, polymer coil of PVP excluded that of Na₂Chs, resulting in increases in chemical potential and adsorption amount of Na₂Chs. It seemed as if Na₂Chs was concentrated by PVP. The concentration effect of non-adsorbable polymer, PVP, on the adsorption amount of Na₂Chs was discussed.