Abstract
Measurement of mechanical properties of a living cell on a scaffold has not been established although various attempts to control the adhesion between a cell and the scaffold were carried out utilizing the various processes. This study aims to develop a system to probe the mechanical properties of a cell by pushing the cell with an atomic force microscope cantilever and measure both of the deflection of the probe and the cell itself based on a captured image. PC12 cell adhesions, cultured on a structured scaffold made of polydimethylsiloxane, were measured and the effect of the microstructure was compared. Finally, a strategy to measure the mechanical properties of a cell is discussed.
