Abstract
The mixed lymphocyte culture (MLC) responses were examined among family members including offspring who were born from the mating between father and daughter. The lymphocytes from three inbred offspring did not induce MLC responses in lymphocytes from both father and mother monkeys but parent's lymphocytes could stimulate the lymphocytes from offspring. These three offspring included two half-blood sibling whose lymphocytes did not stimulate each other. This result suggests that these three inbred monkeys might be MHC homozygote but two monkeys might share the same MHC.
