Abstract
Aerobic training at moderate intensity such as the lactate threshold was found to be effective in lowering resting blood pressure in hypertensive patients. Moreover, several studies have also reported on the favorable effects of exercise training in elderly hypertensive patients with or without pharmaceutical drug therapy. However, there is the variation in the depressor response to the exercise therapy among the patients. In order to clarify the factor that contribute the variability in the depressor response among hypertensive individuals, we analyzed the data from 122 hypertensive patients who performed same exercise therapy. We obtained the results that variations in the depressor response to exercise therapy were partly determined by baseline MBP, suggesting the possible involvement of other factors, including genetic factors. Thus we are trying to search the link between the genetic factors and the variation in the depressor response. [Jpn J Physiol 54 Suppl:S31 (2004)]
